Fatigue after pfizer first dose12/29/2023 One North Carolina woman in the Moderna study who is in her 50s said she didn't experience a fever but suffered a bad migraine that left her drained for a day and unable to focus. "It's a simple fact that some vaccines are more unpleasant to take than others," Stat News' Helen Branswell recently wrote. If approved, the Covid-19 vaccine would not be the first to cause short-term pain and discomfort in some recipients. Infectious disease specialist Florian Krammer of New York's Mount Sinai said on Twitter that the side effects reported in Moderna's phase one trial are " unpleasant but not dangerous." It remains to be seen whether kids and pregnant women will experience similar symptoms. As companies progressed through clinical trials, several vaccine makers abandoned their highest doses following reports of more severe reactions. Moderna and Pfizer have acknowledged that their vaccines could induce side effects that are similar to symptoms associated with mild Covid-19, such as muscle pain, chills and headache. Likewise, one participant in the Pfizer trial said he experienced more severe symptoms than he expected. Two other participants in the Moderna trial, who asked to remain confidential because they feared backlash from the company, reported similar side effects. 16 that he experienced "full-on Covid-like symptoms." He said the pain in his arm, where he received the shot, felt like a "goose egg on my shoulder." He hardly slept that night, recording that his temperature was higher than 100 degrees for five hours.Īfter 12 hours, Hutchison said he felt back to normal and his energy levels returned. Having signed a lengthy consent form, Hutchison was aware that he might experience symptoms. But he was still struck by the severity and duration, tweeting on Sept. Eight hours later, he said he was bed bound with a fever of over 101, shakes, chills, a pounding headache and shortness of breath. He got his second shot at a clinic on Sept. 18, he said he felt a little under the weather for several days with a low-grade fever. While still experimental, mRNA vaccines potentially offer faster development and production times, which could be a major benefit during a global pandemic that has led to more than 1 million fatalities.Īfter getting the first shot on Aug. He specifically wanted to support Moderna's effort, as he was intrigued by the company's RNA-based approach. Hutchison, a 44-year-old computational biologist in Utah, said he signed up for Moderna's phase three trial because he's healthy, physically fit and a big believer in vaccines. The trials are also still ongoing, so it remains to be seen how many participants who received the vaccine will report side effects. But Pfizer said it was in a minority of its cases. While it's possible some of the symptoms described could be attributed to an unrelated illness, Moderna and Pfizer previously said some participants in their phase one trials experienced mild Covid-19 symptoms. The health care worker administering the vaccine is also in the dark. The trials, which each have tens of thousands of participants, are double-blind, meaning half of them are receiving saline or another placebo and patients don't know what treatment they are receiving. Personal Loans for 670 Credit Score or Lower Personal Loans for 580 Credit Score or Lower Best Debt Consolidation Loans for Bad Credit
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